Card 1 · Sepsis screen and neuro
SIRS criteria
Four quick signs that the body is mounting a systemic inflammatory response. Two or more of the four meet the definition of SIRS; in the 1991 consensus definitions, sepsis was SIRS plus a documented or suspected infection.
| Sign | Threshold |
|---|---|
| Temperature | Above 38 °C, or below 36 °C |
| Heart rate | Above 90 beats per minute |
| Breathing | Respiratory rate above 20 per minute, or an arterial CO2 (PaCO2) below 32 mm Hg |
| White blood cells | Above 12,000 per µL, or below 4,000 per µL, or more than 10% immature (band) forms |
How it reads
- SIRS present
- 2 or more of the 4 criteria
- Not SIRS
- 0 or 1 criterion
- The criteria come from the 1991 consensus conference of the American College of Chest Physicians and the Society of Critical Care Medicine, published in 1992. They were chosen because each is quickly available at the bedside.
- SIRS can be caused by things other than infection, such as trauma, burns or pancreatitis. The criteria describe the response, not its cause.